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Caryophyllene: The Pepper Mill of Cannabis
The Journal
PrimerMarch 31, 20265 min readCaryophyllene

Caryophyllene: The Pepper Mill of Cannabis

The only terpene that also acts as a cannabinoid. Translation: it tastes like black pepper and feels like a hug.

By Terroir Editors

Caryophyllene is the only terpene that is also, properly speaking, a cannabinoid. It binds to the body’s CB2 receptors directly, which is why a peppery flower can feel calmly anti-inflammatory in a way a mango-forward one cannot. The kitchen version of this molecule is the black peppercorn — the same compound that makes a pepper grinder smell like a pepper grinder.

Cannabis examples: Original Glue (GG4), Bubba Kush, Sour Diesel (caryophyllene as a secondary), Purple Punch. The signature you’re looking for is a spicy-warm nose with a slight gasoline edge.

What it pairs with

This is the terpene to reach for when the meal is bold and the wine list is Syrah, Côte-Rôtie, Barolo.

  • Steak au poivre. A crust of crushed black pepper, a brandy-cream pan sauce, frites. The pepper crust on the steak is literally the same molecule as the dominant terpene in the flower. Pairing as tautology.
  • Italian sausage and broccoli rabe over orecchiette. Fennel seed, chili flake, garlic, bitter greens. The fennel and chili echo the pepper, the bitterness gives the strain something to push against.
  • Carne asada tacos with a smoked salsa. The smoke is the bridge. Char on the meat, char on the salsa, peppery resin in the strain. Eat them standing up.

The body note

Because caryophyllene engages CB2 directly, it tends to feel less up and less out; more in. This is the strain category we recommend for after a long day on your feet. Roll something small, eat something heavy, sit through whatever you wanted to watch.

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